"Decoding Drug Nomenclature: Understanding Prefixes and Suffixes in Pharmaceutical Terminology"
Pharmaceuticals play a crucial role in modern medicine, and a clear understanding of drug names is essential for healthcare professionals and patients alike. However, many drug names can seem like a foreign language to the uninitiated. That's where prefixes and suffixes come in. These linguistic components provide valuable information about the origin, composition, and purpose of a drug. In this blog, we'll explore the most common drug prefixes and suffixes, demystifying their meanings and helping you to make sense of those confusing pharmaceutical labels. So whether you're a student studying pharmacology, or simply someone who wants to have a better understanding of their medication, this guide is for you.
​STEM | DEFINITION OR CLASS | EXAMPLES |
​-ac | NSAID (acetic acid derivatives) | bromfenac, dexpemedolac |
-adol- | Mixed opiate receptor agonists/antagonists | levonantradol, spiradoline, tazadolene |
-afil | Inhibitor of PDE5 with vasodilator action | ​sildenafil (viagra), tadalafil |
-alol | ​Combined alpha and beta blockers | labetalol, medroxalol |
-andr- | ​Androgens | ​nandrolone |
-anib | ​Angiogenesis inhibitors | ​Pazopanib, Vandetanib |
-anserin | Serotonin 5-HT (sub) 2 receptor antagonists | ​altanserin, tropanserin |
-arabine | ​Antineoplastics | ​fludarabine |
-ase | ​Enzymes | ​alglucerase, dornase alfa |
-atadine | ​Tricyclic anti-asthmatics | ​olopatadine, loratadine |
-axine | ​Antianxiety, antidepressant | ​venlafaxine |
-azenil | ​Benzodiazepine receptor agonists/antagonist | ​bretazenil, flumazenil |
-pam | ​Anti-anxiety | ​lorazepam, diazepam |
-azepide | ​Cholecystokinin receptor antagonists | ​devazepide |
-azocine | ​Narcotic antagonists/agonists | ​quadazocine, ketazocine |
-azoline | ​Antihistamines/local vasoconstrictors | ​antazoline |
-azosin | ​Antihypertensives | ​doxazosin |
-bactam | ​Beta-lactamase inhibitors | ​sulbactam |
-bamate | ​Tranquilizers/antiepileptics | ​meprobamate, felbamate |
-barb- | ​Barbituric acid derivatives | ​phenobarbital, secobarbital |
-bersat | ​Anticonvulsants; antimigraine | ​carabersat; tidembersat |
-bufen | NSAID | ​indobufen |
-butan | Antiseptics | ​dapabutan, lopbutan |
-zone | ​Anti-inflammatory analgesics | ​mofebutazone |
-caine | ​Local anesthetics | ​lidocaine, dibucaine |
​-carbef | ​Antibiotics | loracarbef |
​-cillin | ​Antibiotics | ​ampicillin, penicillin |
​-cog | ​Blog coagulation factors | ​eptacog alfa, nonacog alfa, octocog alfa |
​-zole | ​Antifungals | ​fluconazole, oxiconazole |
-cort- | ​Corticosteroid | ​hydrocortisone |
​-curium | ​Neuromuscular blocking agents | ​atracurium |
​-cyline | ​Antibiotics (tetracycline type) | ​minocycline, tetracyline |
​-dralazine | Antihypertensives | ​hydralazine |
​-dronate | ​Calcium metabolism regulators | ​etidronate, tiludronate |
​-ectin | ​Antiparasitics | ​doramectin, moxidectin |
​-erg- | ​Ergot alkaloid derivatives | ​pergolide |
​-ide | ​Diuretics | ​bumetanide, furosemide |
​-fenamic | ​Anti-inflammatory | ​mefenamic acid, flufenamic acid |
​-fentanil | ​Narcotic analgesics | ​alfentanil, mirfentanil |
​-fibrate | ​Antihyperlipidemics | ​bezafibrate |
​-flurane | ​Inhalation anesthetics | ​enflurane, isoflurane |
​-gest- | ​Progestins | ​megestrol |
​-giline | ​MAO-inhibitors | ​selegiline |
​-gillin | ​Antibiotics | ​mitogillin |
​-gliptin | ​Antihyperglycemics | ​vildagliptin |
​-glitazar | ​Antihyperglycemics | ​farglitazar |
​-flizatone | ​Antihyperglycemics | ​ciglitazone, rosiglitazone |
​-grel- | ​Platelet aggregation inhibitor | ​clopidogrel, ticagrelor |
​-imex | ​Immunostimulants | ​forfenimex, roquinimex |
​-imus | ​Immunosuppressives | ​tacrolimus, napirimus, gusperimus |
​-irudin | ​Anticoagulants | ​desirudin |
​-leukin | ​Interleukin-2 derivatives | ​teceleukin, aldesleukin |
​-lukast | ​Leukotriene antagonists | ​montelukast, zafirlukast |
​-mab | ​Monoclonal antibodies | ​capromab, daclizumab, detumomab |
​-mantadine | ​Antivirals | ​rimantadine |
​-milast | ​Antiasthmatics/antiallergics | ​piclamilast |
​-monam | ​Monobactam antibiotics | ​gloximonam |
​-mustine | ​Antineoplastics | ​carmustine |
​-mycin | ​Antibiotics | ​lincomycin |
​-olol | ​Betablockers | ​timolol, atenolol |
​-one | ​Steroids | ​minaxolone, prednisolone |
​-orphan | ​Narcotic antagonists/agonists | ​methrorphan, dextrorphan |
​-oxacin | ​Antibiotics | ​dilfoxacin, ciprofloxacin |
​-oxetine | ​Antidepressants | ​duloxetine, reboxetine |
​-pamide | ​Diuretics | ​adipamide |
​-pamil | ​Coronary vasodilators | ​tiapamil |
​-parin | ​Heparin derivatives | ​heparin, tinzaparin, dalteparin |
​-peridol | ​Antipsychotics | ​haloperidol |
​-peridone | ​Antipsychotics | ​risperidone, iloperidone |
​-pidem | ​Hypnotics/Sedatives | ​zolpidem, alpidem |
​-piridine | ​Cognition enhancers | ​linopiridine, besipiridine |
​-poetin | ​Erythropoietins | ​epoetin alfa, epoetin beta |
​-pramine | ​Antidepressants | ​lofepramine |
​-prazole | ​Proton-pump inhibitor | ​omeprazole, lansoprazole |
​-pred- | ​Prednisone derivatives | ​prednicarbate, cloprednol |
​-pril | ​Antihypertensive | ​captopril, lisinopril, enalapril |
​-profen | ​Anti-inflammatory/analgesics | ​flurbiprofen, ibuprofen |
​-prost- | ​Prostaglandin analogue | ​latanoprost, unoprostone |
​-rubicin | ​Antineoplastic antibiotics | ​epirubicin, idarubicin |
​-sartan | ​Angiotensin II receptor antagonists | ​losartan, eprosartan, irbesartan |
​-statin | ​HMG-CoA reductase inhibitors | ​atorvastatin, fluvastatin, lovastatin |
​-one | ​Steroids | ​testosterone |
​-sulfa | ​Antibiotics | ​sulfasalazine |
​-tegrast | ​Antiasthmatics/antiallergics | ​Valategrast |
​-terol | ​Bronchodilators | ​albuterol |
​-thiazide | ​Diuretics | ​chlorothiazide, hydrochlorothiazide |
​-tide | ​peptides and glycopeptides | ​Nesiritide, Octreotide |
​-tocin | ​Oxytocin | ​Oxytocin, pitocin |
​-trexate | ​Antimetabolites | ​methotrexate |
​-triptyline | ​Antidepressants | ​amitriptyline |
-uracil | ​Thyroid antagonist and antineoplastic | ​fluorouracil |
​-zolast | ​Antiasthmatics | ​eclazolast, ontazolast |
​cef- | ​Cephalosporins | ​cefazolin |
​estr- | ​Estrogens | ​estrone |
-​vir | ​Antiviral | ​viroxime, acyclovir, oseltamivir |
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